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Tomas Vanecek Selected Research

Familial cylindromatosis

2/2016The CYLD p.R758X worldwide recurrent nonsense mutation detected in patients with multiple familial trichoepithelioma type 1, Brooke-Spiegler syndrome and familial cylindromatosis represents a mutational hotspot in the gene.
2/2013A clinicopathologic and molecular biologic study of patients presenting with few adnexal tumors (two to four) from the morphological spectrum of Brooke-Spiegler syndrome.
8/2011Recurrent CYLD nonsense mutation associated with a severe, disfiguring phenotype in an African American family with multiple familial trichoepithelioma.

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Tomas Vanecek Research Topics

Disease

24Neoplasms (Cancer)
02/2022 - 07/2004
3Renal Cell Carcinoma (Grawitz Tumor)
02/2017 - 02/2013
3Familial cylindromatosis
02/2016 - 08/2011
2Metaplasia
09/2020 - 08/2007
2Adenocarcinoma
09/2020 - 03/2020
2Noninfiltrating Intraductal Carcinoma (DCIS)
10/2019 - 11/2018
2Salivary Gland Neoplasms (Salivary Gland Cancer)
10/2019 - 11/2018
2Basal Cell Carcinoma (Rodent Ulcer)
06/2017 - 05/2009
2Neoplasm Metastasis (Metastasis)
12/2014 - 08/2009
2Seminoma
04/2014 - 05/2006
2Carcinoma (Carcinomatosis)
01/2014 - 05/2009
2Tuberous Sclerosis (Bourneville's Disease)
12/2012 - 08/2009
2Carcinogenesis
05/2009 - 11/2007
1Kidney Neoplasms (Kidney Cancer)
01/2022
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2021
1Carney Triad
01/2021
1Villous Adenoma
09/2020
1Calcinosis
01/2019
1Phyllodes Tumor (Cystosarcoma Phylloides)
06/2017
1Intraductal Papilloma
06/2017
1Acrospiroma
06/2017
1Fibroadenoma
06/2017
1Necrosis
02/2017
1Retinoblastoma (Glioblastoma, Retinal)
01/2017
1Mammary Analogue Secretory Carcinoma
01/2014
1Angiofibroma
12/2012
1Lymphedema (Milroy Disease)
12/2012
1Placental Site Trophoblastic Tumor
07/2010
1Autosomal Dominant Polycystic Kidney (ADPKD)
08/2009
1Adenoma (Adenomas)
05/2009
1Leydig Cell Tumor
10/2008
1Malignant Mixed Tumor (Tumor, Malignant Mixed)
07/2007
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
10/2006
1Lymphoma (Lymphomas)
10/2006
1Pseudolymphoma
10/2006
1Ovarian Neoplasms (Ovarian Cancer)
05/2006
1Testicular Neoplasms (Testicular Cancer)
05/2006
1Hyperplasia
10/2005

Drug/Important Bio-Agent (IBA)

7S100 Proteins (S 100 Protein)IBA
10/2019 - 07/2004
5Biological ProductsIBA
01/2021 - 12/2009
5VimentinIBA
12/2014 - 07/2004
5Proteins (Proteins, Gene)FDA Link
06/2010 - 03/2005
4AntibodiesIBA
01/2017 - 07/2004
3trans-sodium crocetinate (crocetin)IBA
01/2022 - 08/2009
2DNA (Deoxyribonucleic Acid)IBA
01/2017 - 05/2009
2Nonsense Codon (Nonsense Mutation)IBA
02/2016 - 08/2011
2Messenger RNA (mRNA)IBA
04/2014 - 02/2013
2ParaffinIBA
02/2013 - 06/2010
2Formaldehyde (Formol)FDA Link
02/2013 - 06/2010
2Periodic AcidIBA
05/2010 - 05/2006
2Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
10/2006 - 10/2005
2T-Cell Antigen Receptors (T-Cell Receptor)IBA
10/2006 - 10/2005
1Mechanistic Target of Rapamycin Complex 1IBA
01/2022
1Succinate Dehydrogenase (Fumarate Reductase)IBA
01/2021
1Colloids (Colloid)IBA
09/2020
1Pemetrexed (MTA)FDA Link
03/2020
1Bevacizumab (Avastin)FDA Link
03/2020
1nintedanibIBA
03/2020
1CrizotinibIBA
03/2020
1CalciumIBA
01/2019
1Phosphates (Orthophosphate)IBA
01/2019
1Inosine Diphosphate (IDP)IBA
06/2017
1Capsules (Microcapsules)IBA
02/2017
1Retinoblastoma ProteinIBA
01/2017
1Keratins (Keratin)IBA
03/2015
1N-acetyltalosaminuronic acid (NAT)IBA
12/2014
1Human beta Subunit Chorionic GonadotropinIBA
04/2014
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
04/2014
1CateninsIBA
01/2014
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
02/2013
1Mitogen-Activated Protein KinasesIBA
02/2013
1Calbindin 2IBA
07/2010
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
07/2010
1Inhibins (Inhibin)IBA
07/2010
1Placental Lactogen (Human Placental Lactogen)IBA
07/2010
1Mucin-1 (CA 15-3 Antigen)IBA
07/2010
1Keratin-7 (Cytokeratin 7)IBA
07/2010
1Keratin-20 (Cytokeratin 20)IBA
07/2010
1placental alkaline phosphataseIBA
07/2010
1mucicarmineIBA
05/2010
1Glycogen Synthase (Synthase I)IBA
05/2009
1beta CateninIBA
05/2009
1Dinoprostone (PGE2)FDA Link
10/2008
1Prostaglandin-E SynthasesIBA
10/2008
1ProstaglandinsIBA
10/2008
1Tyrosine (L-Tyrosine)FDA Link
11/2007
1Phosphotransferases (Kinase)IBA
11/2007
1Tyrosine Kinase InhibitorsIBA
11/2007
1MucinsIBA
08/2007
1GlycogenIBA
05/2006
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
05/2006
1CollagenIBA
10/2005
1AmylasesFDA Link
05/2005
1Phosphopyruvate Hydratase (Enolase)IBA
05/2005
1DesminIBA
07/2004
1CalponinsIBA
07/2004

Therapy/Procedure

2Therapeutics
02/2022 - 02/2013
1Combination Drug Therapy (Combination Chemotherapy)
03/2020
1Neck Dissection (Radical Neck Dissection)
08/2009